Representative Papers on Drug Design and Synthesis

♣ JungWha Yoon, HyeYoung Choi, Hyun Joo Lee, Chong Hyun Ryu, Hyeung-geun Park, Young-ger Suh, Uhtaek Oh, Yeon Su Jeong, Jin Kyu Choi, Young-Ho Park, Hee-Doo Kim, Chain-branched Acyclic Phenethylthiocarbamates As Vanilloid Receptor Antagonists , Bioorganic & Medicinal Chemistry Letters,13, 1549-1552 (2003). [Full text-PDF]

♣ Ju-Hyun Park; Myung-Hee Choi; Lak Shin Jeong; Moon Woo Chun; Hee-Doo Kim,Synthesis of [1'-fluoro-2',2'-bis-(hydroxymethyl)cyclopropylmethyl]purines as Antiviral Agents, Nucleosides & Nucleotides, and Nucleic acids, 22(5&8), 955 - 957(2003). [Full text-PDF]

♣ Ju-Hyun Park; Young Rang Lee; Moon Woo Chun; Lak Shin Jeong; Chong-Kyo Lee; Hee-Doo Kim, Synthesis of (z)-(1-Fluoro-2-hydroxymethyl-cyclopropylmethyl)purines, Nucleosides & Nucleotides, and Nucleic acids, 22(5&8), 659 - 661(2003).[Full text-PDF]

♣Chong Hyun Ryu, Mijung Jang, Jeong Wha Jung, Ju Hyun Park, HyeYoung Choi, Young-ger Suh, Uhtaek Oh, Hyeung-geun Park, Jeewoo Lee, Young-Ho Park,Yeon Su Jeong, Jin Kyu Choi, Yung-Hyup Joo, Hee-Doo Kim, Chain-branched 1,3-Dibenzylthioureas As Vanilloid Receptor 1 Antagonists, Bioorg. & Med. Chem. Lett., 14,1751-1755 (2004).[Full text-PDF]

♣Minsun Chang; Seol-Rin Park; Juhyun Kim; Mijung Jang; Jeong Hyun Park; Ji Eun Park; Hyeung-Geun Park; Young-Ger Suh; Yeon Su Jeong; Young-Ho Park; Hee-Doo Kim, Silicon switch approach in TRPV1 antagonist MK-056 and its analogues, Bioorg. & Med. Chem., 18,111-116 (2010).[Full text-PDF]

♣Seol-Rin Park; Juhyun Kim; Sun Young Lee; Young-Ho Park; Hee-Doo Kim, 2-Methylacrylamide as a Bioisoster of Thiourea Group for 1,3-Dibenzylthioureido TRPV1 Receptor Antagonists, Bioorg. & Med. Chem.Lett., 28, 2080-2083 (2018).[Full text-PDF]